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Instruments

The NCQBCS is outfitted with several state-of-the-art mass spectrometry systems. These instruments are used on the various ongoing technology development projects. Improvements made on these devices are then easily disseminated to current commercial instruments. Further, collaborator projects are also conducted on the very same equipment ensuring the best results possible.

 

Instrumentation list

Our Equipment

Instruments we use in our lab

         

         

Lumos Fusion Orbitrap with ETD

These systems have the latest generation atmospheric pressure inlets for high sensitivity ion injection. They are outfitted with a high resolution mass filtering quadrupole, a high field Orbitrap mass analyzer, and a dual cell quadrupole linear ion trap. The systems are capable of collisional dissociation – beam type and ion trap – and electron transfer dissociation (ETD).  Some of our systems can also do activated ion-ETD (AI-ETD) and infrared multiphoton dissociation (IRMPD).

More info

Q-Exactive HF

This system contains a quadrupole mass filter along with a high field Orbitrap mass analyzer. It is useful for proteomic and metabolomic applications.

More info

         
         

 

Q-Exactive Focus

Like the Q-Exactive HF, this system is a hybrid quadrupole mass filter with Orbitrap analyzer. The main difference is that the Orbitrap analyzer does not offer the same high resolution analysis options as the higher end Orbitrap analyzers. It is used mostly for small molecule analysis.

More info

Orbitrap Elite with ETD

This system features a dual cell linear ion trap for precursor ion isolation and MS/MS analysis, among other functions. Ions are passed to a high field Orbitrap mass analyzer. This system has been modified to perform AI-ETD, negative ETD, IRMPD, and has a modified Orbitrap analyzer that can achieve resolving powers in excess of one million.

More info

         
         

Q-Exactive GC

Our laboratory coupled the first GC to an Orbitrap analyzer in 2010. We now have a commercial version of this initial system that offers routine metabolite profiling at high mass accuracy owing to the high field Orbitrap mass analyzer in the system.

More info

         

Quantiva Triple Quadrupole

These systems are connected to liquid chromatography systems and contain an electrodynamic ion funnel and the high resolution quadrupole mass filters.

More info

         
         

LTQ Velos with ETD

This dual cell linear ion trap system is great for development work and method optimization.

More info

         

Contact

For additional information about NCQBCS please send your contact details using the form below.
Note, if you are interested in training, please use the form on our training page.

Contact

For additional information about NCQBCS please send your contact details using the form below.
Note, if you are interested in training, please use the form on our training page.


Where we are

425 Henry Mall, Coon Lab 4462, Madison WI

777 Highland Avenue, Li Lab 5234, Madison, WI

330 N. Orchard Street, Pagliarini Lab 2268, Madison WI

 

How to contact us

Email address: laura.vantoll@wisc.edu