07 Oct 2019

Biomedical Projects Library

     

07 Oct 2019
Biomedical Projects Publication Library

 

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Cell type specific gene therapy confers protection against motor neuron disease caused by a TFG variant

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Pptc7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy

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Plasma metabolomics supports non-fasted sampling for metabolic profiling across a spectrum of glucose tolerance in the Nile rat model for type 2 diabetes

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MmuPV1 E6 induces cell proliferation and other hallmarks of cancer

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A transcriptional network governing ceramide homeostasis establishes a cytokine-dependent developmental process

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Hem25p is required for mitochondrial IPP transport in fungi

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HIV-1 virological synapse formation enhances infection spread by dysregulating Aurora Kinase B

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Decreased plasma cartilage acidic protein 1 in COVID-19

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The citrate transporters SLC13A5 and SLC25A1 elicit different metabolic responses and phenotypes in the mouse

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Large‐scale proteome and metabolome analysis of CSF implicates altered glucose and carbon metabolism and succinylcarnitine in Alzheimer’s disease

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Aim18p and Aim46p are chalcone isomerase domain-containing mitochondrial hemoproteins in Saccharomyces cerevisiae

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N-glycoproteomics of brain synapses and synaptic vesicles

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Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut

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Structure and functionality of a multimeric human COQ7:COQ9 complex

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Spatial Snapshots of Amyloid Precursor Protein Intramembrane Processing via Early Endosome Proteomics

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Isotopic N,N-dimethyl leucine tags for absolute quantification of clustering and apolipoprotein E in Alzheimer’s disease

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The transcriptional elongation factor CTR9 demarcates PRC2-mediated H3K27me3 domains by altering PRC2 subtype equilibrium

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12-Plex DiLeu Isobaric Labeling Enabled High-Throughput Investigation of Citrullination Alterations in the DNA Damage Response

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Rapid and Gentle Immunopurification of Brain Synaptic Vesicles

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Increased expression of SLC25A1/CIC causes an autistic-like phenotype with altered neuron morphology

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SLC13A5/sodium-citrate co-transporter overexpression causes disrupted white matter integrity and an autistic-like phenotype

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Defining intermediates and redundancies in coenzyme Q precursor biosynthesis

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Pilot Proteomic Analysis of Cerebrospinal Fluid in Alzheimer’s Disease

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Large-Scale Multi-omic Analysis of COVID-19 Severity

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Multi-Omic Single-Shot Technology for Integrated Proteome and Lipidome Analysis

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A large-scale genome–lipid association map guides lipid identification

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Quantitative shotgun proteome analysis by direct infusion

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Argonaut: A Web Platform for Collaborative Multi-omic Data Visualization and Exploration

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A Genetic Toggle for Chemical Control of Individual Plk1 Substrates

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In-depth Quantification of Extracellular Matrix Proteins from Human Pancreas

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A Strategy for Discovery and Verification of Candidate Biomarkers in Cerebrospinal Fluid of Preclinical Alzheimer’s Disease

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Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis

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Polo-like Kinase 4 Maintains Centriolar Satellite Integrity By Phosphorylation Of Centrosomal Protein 131 (CEP131)

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Quantitative Proteomic Analysis of a Genetically Induced Prostate Inflammation Mouse Model via Custom 4-plex DiLeu Isobaric Labeling

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Proteomic Atlas of the Human Brain in Alzheimer’s Disease

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An Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis

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Systems Analyses Reveal Physiological Roles and Genetic Regulators of Liver Lipid Species

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Genetic Regulation of Plasma Lipid Species and Their Association with Metabolic Phenotypes

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Islet proteomics reveals genetic variation in dopamine production resulting in altered insulin secretion

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ATM directs DNA damage responses and proteostasis via genetically separable pathways

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Large-Scale Differentiation and Site Specific Discrimination of Hydroxyproline Isomers by EThcD Mass Spectrometry

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Caloric restriction engages hepatic RNA processing mechanisms in rhesus monkeys

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Multi-omics reveal specific targets of the RNA-binding protein Puf3p in mitochondrial biogenesis

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Multi-omic mitoprotease profiling defines a role for Oct1p in coenzyme Q production

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A split-Abl kinase for direct activation in cells

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Ptc7p dephosphorylates select mitochondrial proteins to enhance metabolic function

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Multi-omics evidence for inheritance of energy pathways in red blood cells

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NeuCode proteomics reveals Bap1 regulation of metabolism

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Site-specific characterization and quantitation of N-glycopeptides (EThcD)

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PKM2 methylation by CARM1 activates aerobic glycolysis

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A Combined Isobaric and Mass Difference Quantification Strategy (mdDiLeu)

 

 

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