university of wisconsin-madison

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Gut microbiome may play a role in brain functions and behaviors

Gut microbiota can regulate host physiological and pathological status through gut–brain communications or pathways. However, the impact of the gut microbiome on the proteins involved in regulating brain functions and behaviors is still not clearly understood. In a recent publication by Liu et al., the author describes a combined label-free and 10-plex DiLeu-based quantitative method that enabled a comprehensive profiling of gut microbiome that induced dynamic changes, suggesting that the gut microbiome might mediate a range of behavioral changes, brain development, and learning and memory through these neuropeptides and proteins.

Liu R et al. Integrated Label-Free and 10-plex DiLeu Isobaric Tag Quantitative Methods for Profiling Changes in the Mouse Hypothalamic Neuropeptidome and Proteome: Assessment of the Impact of the Gut Microbiome. Analytical Chemistry.

Summer School Registration Closes Soon

Registration for the 3rd Annual North American Mass Spectrometry Summer School will close on March 1.

This means time is running out to sign up for 4 free days of learning, tutorial lectures, and hands-on-workshops– all led by world-leading experts in mass spectrometry.

The goal of this event– which will take place from June 15-18 at the Wisconsin Institute for Discovery– is to provide an engaging and inspiring program to students by combining networking, education and discovery and housing it all under one roof.

Specifically, this program covers the latest in application of mass spectrometry to omic analyses, from both industry and academic lenses. With tutorial lectures covering a variety of topics, from mass analyzers to lipidomics, and hands-on-workshops aimed at both scientific and professional development, this program is not one you would want to miss. Don’t forget to tell your peers about this excellent opportunity!

Registration is available at the following link:

The ‘Ice Road Truckers of Science’ and Why We Need Them

Authors Rebecca Blank, chancellor of the University of Wisconsin-Madison, and Brad Schwartz, CEO of Morgridge Institute for Research in Madison, call for a scientific renaissance regarding American policy choices. Their article “The ‘Ice Road Truckers of science’ and why we need them”, featured in The Hill, reminisces on a time when American science dominated the world because of the US government’s commitment to funding basic research at a level higher than all other countries. That commitment made Nobel Prize winning discoveries possible and resulted in tremendous gains for the global community. Blank and Schwartz warn that if American policy choices continue to “sacrifice the opportunity to make [such] discoveries, then [America] will become one of the nations that must figure out how to make someone else’s inventions cheaper, instead of leading the market by capitalizing on new knowledge.”

Please read the article for yourself, here