Label-free

Sometimes it is convenient not to use any isotope label at all for protein quantification.  This is an emerging approach for proteomics and we have considerable experience in the best practices. If you’d like to learn more about label-free quantification sample prep, MS methodology, or data processing give us a call.

Metabolic labeling

Metabolic labels offer a unique avenue to incorporate the isotopes during protein synthesis and, thus, eliminate many of the common sample preparation errors of mixing. Whether you have interest in traditional SILAC or multi-plexed NeuCode, we’ve got your covered.    

Isobaric Chemical Labeling

Isobaric chemical labels offer a path for high-throughput, multi-plexed proteome analysis.  We extensive experience with TMT and DiLeu labeling including sample preparation, labeling, associated MS Methods, and data analysis.