Lipidomics Schedule


Schedule


August 2, 2024

IN-PERSON, School of Pharmacy, 1116 Rennebohm Hall, University of Wisconsin-Madison
and ZOOM
All times are in CST time zone (Chicago)
Schedule subject to change

9:00-10:00 – Fundamentals and overview of chemical labeling approaches to quantitative proteomics
Zicong Wang and Peng-Kai Liu – Lingjun Li Lab at the School of Pharmacy, University of Wisconsin-Madison

10:00-11:00 – Data processing and analysis
Dr. Haiyan Lu and Feixuan Wu – Lingjun Li Lab at the School of Pharmacy, University of Wisconsin-Madison

11:00-12:00 – High-throughput quantitative top-down proteomics using intact protein-level tandem mass tag (TMT) labeling
Dr. Si Wu – University of Alabama

12:00-1:00 – Lunch break (Pizza will be provided for in-person attendees)

12:30-1:00 – Platforms and resources for proteomics and beyond
Dr. Tao Chen – Absea Biotechnology Ltd.

1:15-2:15 – Applications of DiLeu tags for quantitative PTM analysis and biomarker discovery
Dr. Haiyan Lu and Feixuan Wu – Lingjun Li Lab at the School of Pharmacy, University of Wisconsin-Madison

2:15-3:15 – Development and application of isobaric tags for quantitative glycomics and lipidomics
Zicong Wang and Peng-Kai Liu – Lingjun Li Lab at the School of Pharmacy, University of Wisconsin-Madison

3:15-3:30 – Break

3:30-4:30 – Unlocking the secrets of complex proteotypes with sample multiplexing-based quantitative proteomics
Dr. Qing Yu – Harvard Medical School

4:30-5:00 – Q & A and discussion

Lipidomics Registration


Registration

This workshop will be offered both IN PERSON (1116 Rennebohm Hall, School of Pharmacy, UW-Madison) and Via Zoom (zoom link will be sent to registered attendees)

There is no registration fee, however if you register you have made a commitment to attend.

If attending via Zoom, we ask that you turn on your camera in order to make this an interactive session.

We will be recording this workshop on Zoom, as part of the registration process you will need to consent to being recorded.

We will post the recordings on YouTube, so you will have access to the material after the workshop.

Registration is Closed for the Workshop

If you have questions or difficulty in registering, please email Laura.

This event is made possible by generous funding from the National Institutes of Health National Center for Quantitative Biology of Complex Systems (2P41GM108538).

Lipidomics Masthead

 

 

 

Chemical Tags for Quantitative Omics Workshop

 
August 2, 2024 in-person and via Zoom
This interactive workshop will cover the fundamentals of chemical tagging for mass spectrometry, through a mix of lectures, demos and discussion.

This is an intermediate level workshop, and is open to graduate students, post-docs, faculty and staff who have at least 6 months of mass spec hands-on use and/or experience processing mass spec data.

This event is made possible by generous funding from the National Institutes of Health National Center for Quantitative Biology of Complex Systems (2P41GM108538).

 

Online Resources

Online Resources


Subscribe to our You Tube channel for training videos and lectures from leading scientists in the field.

Open source Software is available to help with data acquisition and analysis.

Follow us on Twitter @Coon_Labs for news of science of interest.

Visit the Biomedical Technology Resources portal, a one stop shop for innovative technology resources supported by NIH funded research centers.

Biomedical Projects Library

Biomedical Projects Publication Library

 

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Cell type specific gene therapy confers protection against motor neuron disease caused by a TFG variant

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Pptc7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy

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Plasma metabolomics supports non-fasted sampling for metabolic profiling across a spectrum of glucose tolerance in the Nile rat model for type 2 diabetes

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MmuPV1 E6 induces cell proliferation and other hallmarks of cancer

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A transcriptional network governing ceramide homeostasis establishes a cytokine-dependent developmental process

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Hem25p is required for mitochondrial IPP transport in fungi

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HIV-1 virological synapse formation enhances infection spread by dysregulating Aurora Kinase B

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Decreased plasma cartilage acidic protein 1 in COVID-19

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The citrate transporters SLC13A5 and SLC25A1 elicit different metabolic responses and phenotypes in the mouse

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Large‐scale proteome and metabolome analysis of CSF implicates altered glucose and carbon metabolism and succinylcarnitine in Alzheimer’s disease

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Aim18p and Aim46p are chalcone isomerase domain-containing mitochondrial hemoproteins in Saccharomyces cerevisiae

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N-glycoproteomics of brain synapses and synaptic vesicles

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Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut

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Structure and functionality of a multimeric human COQ7:COQ9 complex

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Spatial Snapshots of Amyloid Precursor Protein Intramembrane Processing via Early Endosome Proteomics

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Isotopic N,N-dimethyl leucine tags for absolute quantification of clustering and apolipoprotein E in Alzheimer’s disease

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The transcriptional elongation factor CTR9 demarcates PRC2-mediated H3K27me3 domains by altering PRC2 subtype equilibrium

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12-Plex DiLeu Isobaric Labeling Enabled High-Throughput Investigation of Citrullination Alterations in the DNA Damage Response

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Rapid and Gentle Immunopurification of Brain Synaptic Vesicles

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Increased expression of SLC25A1/CIC causes an autistic-like phenotype with altered neuron morphology

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SLC13A5/sodium-citrate co-transporter overexpression causes disrupted white matter integrity and an autistic-like phenotype

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Defining intermediates and redundancies in coenzyme Q precursor biosynthesis

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Pilot Proteomic Analysis of Cerebrospinal Fluid in Alzheimer’s Disease

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Large-Scale Multi-omic Analysis of COVID-19 Severity

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Multi-Omic Single-Shot Technology for Integrated Proteome and Lipidome Analysis

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A large-scale genome–lipid association map guides lipid identification

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Quantitative shotgun proteome analysis by direct infusion

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Argonaut: A Web Platform for Collaborative Multi-omic Data Visualization and Exploration

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A Genetic Toggle for Chemical Control of Individual Plk1 Substrates

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In-depth Quantification of Extracellular Matrix Proteins from Human Pancreas

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A Strategy for Discovery and Verification of Candidate Biomarkers in Cerebrospinal Fluid of Preclinical Alzheimer’s Disease

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Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis

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Polo-like Kinase 4 Maintains Centriolar Satellite Integrity By Phosphorylation Of Centrosomal Protein 131 (CEP131)

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Quantitative Proteomic Analysis of a Genetically Induced Prostate Inflammation Mouse Model via Custom 4-plex DiLeu Isobaric Labeling

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Proteomic Atlas of the Human Brain in Alzheimer’s Disease

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An Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis

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Systems Analyses Reveal Physiological Roles and Genetic Regulators of Liver Lipid Species

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Genetic Regulation of Plasma Lipid Species and Their Association with Metabolic Phenotypes

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Islet proteomics reveals genetic variation in dopamine production resulting in altered insulin secretion

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ATM directs DNA damage responses and proteostasis via genetically separable pathways

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Large-Scale Differentiation and Site Specific Discrimination of Hydroxyproline Isomers by EThcD Mass Spectrometry

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Caloric restriction engages hepatic RNA processing mechanisms in rhesus monkeys

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Multi-omics reveal specific targets of the RNA-binding protein Puf3p in mitochondrial biogenesis

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Multi-omic mitoprotease profiling defines a role for Oct1p in coenzyme Q production

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A split-Abl kinase for direct activation in cells

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Ptc7p dephosphorylates select mitochondrial proteins to enhance metabolic function

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Multi-omics evidence for inheritance of energy pathways in red blood cells

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NeuCode proteomics reveals Bap1 regulation of metabolism

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Site-specific characterization and quantitation of N-glycopeptides (EThcD)

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PKM2 methylation by CARM1 activates aerobic glycolysis

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A Combined Isobaric and Mass Difference Quantification Strategy (mdDiLeu)

 

 

Mass Spec Summer School


6th Annual North American Mass Spectrometry Summer School


In-person meeting will be held July 21-24, 2025 at the Discovery Building

Join us for the annual North American Mass Spectrometry Summer School. We are proud to have assembled world-leading experts in mass spectrometry for this three day in-person course. Students will experience an engaging and inspiring program covering fundamentals of mass spectrometry and the latest in its application to the analyses of plants (NSF) and animals (NIH). Tutorial lecture topics include: Mass Analyzers, Ionization, Tandem MS, Proteomics, Metabolomics, Data analysis, and PTMs. Also planned are lectures workshops for scientific and professional development.